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PAβN dihydrochloride

CAS No. 100929-99-5

PAβN dihydrochloride ( MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride )

产品货号. M22016 CAS No. 100929-99-5

PAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥389 有现货
10MG ¥575 有现货
25MG ¥875 有现货
50MG ¥1239 有现货
100MG ¥1855 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PAβN dihydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?
  • 产品描述
    PAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?Moreover, PAβN restores ciprofloxacin susceptibility in five of the ciprofloxacin-resistant isolates.?In addition, clear effects of NMP on the ciprofloxacin MICs are seen for 20 of these ciprofloxacin-resistant isolates.
  • 同义词
    MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Bacterial; efflux pump
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    100929-99-5
  • 分子量
    519.47
  • 分子式
    C25H32Cl2N6O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:95mg/ml (182.88 Mm);H2O:14.29 mg/mL (27.51 mM; Need ultrasonic)
  • SMILES
    Cl.Cl.N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1=CC2=CC=CC=C2C=C1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Lomovskaya O, et al. Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob Agents Chemother. 2001 Jan;45(1):105-16.
产品手册
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