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PAβN dihydrochloride
CAS No. 100929-99-5
PAβN dihydrochloride ( MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride )
产品货号. M22016 CAS No. 100929-99-5
PAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥389 | 有现货 |
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| 10MG | ￥575 | 有现货 |
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| 25MG | ￥875 | 有现货 |
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| 50MG | ￥1239 | 有现货 |
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| 100MG | ￥1855 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PAβN dihydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?
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产品描述PAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?Moreover, PAβN restores ciprofloxacin susceptibility in five of the ciprofloxacin-resistant isolates.?In addition, clear effects of NMP on the ciprofloxacin MICs are seen for 20 of these ciprofloxacin-resistant isolates.
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同义词MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride
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通路GPCR/G Protein
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靶点Antibacterial
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受体Bacterial; efflux pump
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研究领域——
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适应症——
化学信息
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CAS Number100929-99-5
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分子量519.47
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分子式C25H32Cl2N6O2
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纯度>98% (HPLC)
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溶解度DMSO:95mg/ml (182.88 Mm);H2O:14.29 mg/mL (27.51 mM; Need ultrasonic)
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SMILESCl.Cl.N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1=CC2=CC=CC=C2C=C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Polymyxin B nonapept...
Polymyxin B nonapeptide, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probably by binding to the bacterial lipopolysaccharide (LPS)
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PBP 10
Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.
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Methyl α-D-mannopyra...
Methyl α-D-mannopyranoside can be used as an intermediate for chemical sythesis and can ?target macrophages in anti-tuberculosis inhalation therapy.
